pyrazinamide

J - Antiinfectives For Systemic Use -> J04 - Antimycobacterials -> J04A - Drugs For Treatment Of Tuberculosis -> J04AK - Other Drugs For Treatment Of Tuberculosis -> J04AK01 - Pyrazinamide
Administration category: Free Medicine group: antibacterial

Safety margins

≥ 18 years
WeightROADosage
ROA:
po
Dosage:
min. 30mg/kg 1 dd to max. 50mg/kg 1 dd
ROA:
po
Dosage:
to max. 2g/24h in 1 doses

Kidney function

≥ 18 years
ROAGFRDosageIntervalComments
ROA: po
GFR:
<30
Dosage:
standaarddosering 3x per week, max. 2 g per keer, op geleide van de spiegel
Renal elimination: 4-14%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: standaarddosering 3x per week, op geleide van de spiegel

Hemo dialysis: standaarddosering 3x per week, max. 2 g per keer, op geleide van de spiegel; bij hemodialyse toedienen na de dialyse

CAV / VVHD: doseren op geleide van de spiegel

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1711.2
Updated: 02/12/2020 - 22:49
Status: Published

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