tobramycine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01G - Aminoglycoside Antibacterials -> J01GB - Other Aminoglycosides -> J01GB01 - Tobramycin
Administration category: Free Medicine group: antibacterial

Safety margins

≥ 18 years
WeightROADosage
ROA:
iv
Dosage:
min. 5mg/kg 1 dd to max. 7mg/kg 1 dd

Standard dosages

≥ 18 years
WeightROALoadDosage
ROA:
inhalation
Load:
-
Dosage:
300mg 2 dd
Comments:

vernevelvloeistof: 60-75 mg/ml

Kidney function

≥ 18 years
ROAGFRDosageIntervalComments
ROA: iv
GFR:
50 - 80
Interval:
36 Hours
GFR:
30 - 50
Interval:
48 Hours
GFR:
10 - 30
Comments:
doseren op geleide van de serumconcentratie
Renal elimination: 93%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Normale aanvangsdosis, vervolgens interval verlengen op geleide van de spiegel.

Hemo dialysis: Normale aanvangsdosis, vervolgens interval verlengen op geleide van de spiegel. Op dialysedagen: bij toedienen voor dialyse normale dosis; bij toedienen na de dialyse de helft tot een derde van de dosis.

CAV / VVHD: Interval verlengen op geleide van de spiegel.

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1782.2
Updated: 08/16/2017 - 22:03
Status: Published

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